White Paper · Infusion Systems

Beyond Nano: A Performance-First Framework for Cannabis Gummies

Why particle size is not the right benchmark for gummy performance

“Nano” has become shorthand for edible performance, but particle size alone doesn’t guarantee taste, shelf stability or a consistent consumer experience.

Beyond Nano breaks down why delivery-system evidence doesn’t automatically transfer to gummies, and lays out a performance-first framework across four pillars: consumer experience, product quality, manufacturing performance and scientific validation.

Preview page from the Beyond Nano whitepaper

86% preferred Azuca on taste in a blind panel test, vs. 60% for a nano-emulsion gummy.

Over 800 Million Servings Sold ·

A Performance-First Alternative to Particle Size

TiME INFUSION® encapsulates individual cannabinoid molecules within structures that have a hydrophilic, water-friendly exterior, while conventional nano-emulsions suspend clusters of molecules in oil-in-water droplets. By eliminating the emulsion interface, and the surfactants needed to hold it together, TiME INFUSION® helps manufacturers preserve taste, recipe integrity, production efficiency and shelf-life performance in the finished gummy.

What’s Inside

What You'll Learn

Why particle size is an incomplete proxy for gummy performance: Understand what particle size measures, how the nanoscale is defined and why a “nano” label does not establish finished-product performance.

Why gummies create different formulation challenges for nano-emulsions: Learn how water-based emulsions, surfactants and droplet stability can affect gummy recipes, manufacturing processes and finished-product quality.

How infusion systems affect taste, texture and recipe integrity: Explore the potential effects of surfactants, masking agents, water activity and formulation changes on finished-product quality.

What determines cannabis gummy stability over its shelf life: Understand how oxidation, physical instability, syneresis and potency loss can affect gummies over time.

How to evaluate an infusion supplier across four performance pillars: Assess consumer experience, product quality, manufacturing performance and scientific validation in gummies specifically.

What head-to-head gummy testing found: Review findings from an independent blind panel comparing a TiME INFUSION® gummy with a professionally formulated nano-emulsion gummy in the same flavor and dose across taste, texture, effects, overall liking and purchase intent.

Self-Check

Four Questions Every Gummy Manufacturer Should Ask

What does it do to the consumer experience?

Look beyond technical specifications to taste, texture, effects, overall liking and repeat-purchase potential.

What does it do to product quality over its shelf life?

Evaluate potency retention, physical stability, texture and performance under realistic storage conditions.

What does it require from your manufacturing process?

Consider ingredient form, equipment requirements, water activity, solids targets, drying time and production flexibility.

What evidence exists in gummies specifically?

Ask for validation in your actual product format rather than assuming beverage, capsule or ingredient-level data will translate to gummies.

Get The Research

Take a Deeper Look

Beyond Nano

Get the complete performance-first framework, head-to-head gummy findings and the broader clinical, preclinical and real-world research behind TiME INFUSION®.

Download Beyond Nano

Want to Go Deeper?

Explore The Science of Fast-Acting Cannabis Edibles, a companion research report that examines the evidence behind fast-acting edible performance.

The report brings together human pharmacokinetic data, preclinical studies, real-world consumer findings and a blind comparison with a leading nano-emulsion gummy to examine onset, peak effects, consistency across consumers and comparative product performance.

Explore the Data White Paper

About TiME INFUSION®

Azuca® is an applied bioscience company helping brands create differentiated edible and beverage products powered by TiME INFUSION®. TiME INFUSION® individually encapsulates cannabinoid molecules to create a water-friendly ingredient designed for faster, more predictable experiences while preserving finished-product quality.

“We have been carefully, some might say obsessively tracking the space for two years, and we have tried every product that we can get our hands on in the market place. We didn’t personally find that most of them were very effective in terms of delivering quick onset, so we were really looking for a better solution… We found it in Azuca.”Nancy Whiteman, Wana Brands

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